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After summarizing DRESS patients treated with anti-IL-5 agents, Gschwend et al have recommended the administration of an IL-5/IL-5R blockade in the early use in the course of severe DRESS requiring intensive care medicine treatment, with no clinical improvement even using high-dose corticosteroids, with severe concomitant infectious disease, with additional immunosuppressive drugs despite the initiation of high-dose corticosteroids, or with severe and life-threatening organ damage

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