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In addition, large Maf protein such as c-Maf can bind to ARE as homodimers and heterodimers with small Mafs (but not Nrfs) to repress ARE-mediated gene expression [151]

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When a supplier starts with WFI-quality water rather than ordinary purified or distilled water, the entire batch carries a higher baseline of safety before the benzyl alcohol and sterile filtration steps are ever applied